spotfire analysis software (TIBCO)
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TIBCO
spotfire analysis software
Spotfire Analysis Software, supplied by TIBCO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spotfire+analysis+software/spotfire+data+visualization+software/pm40555806-258-7-10
Average 90 stars, based on 1 article reviews
Spotfire Analysis Software, supplied by TIBCO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spotfire+analysis+software/spotfire+data+visualization+software/pm40555806-258-7-10
Average 90 stars, based on 1 article reviews
spotfire analysis software - by Bioz Stars,
2026-09
90/100 stars
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Expressing:Article Title: Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis Article Snippet: .. Unsupervised hierarchical clustering of expression measurements from lncRNAs detected in septic and control patients (top 5% with higher coefficient of variation) was performed using UPGMA clustering and Pearson correlation as a distance measurement in the Control:Article Title: Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis Article Snippet: .. Unsupervised hierarchical clustering of expression measurements from lncRNAs detected in septic and control patients (top 5% with higher coefficient of variation) was performed using UPGMA clustering and Pearson correlation as a distance measurement in the Software:Article Title: Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis Article Snippet: .. Unsupervised hierarchical clustering of expression measurements from lncRNAs detected in septic and control patients (top 5% with higher coefficient of variation) was performed using UPGMA clustering and Pearson correlation as a distance measurement in the Article Title: Digital analysis of blood samples to determine efficacy of cancer therapies for specific cancers Article Snippet: Data is collected and analyzed using TIBCO® Spotfire® analysis software. .. Data is collected and analyzed using Article Title: CRISPR protein inhibitors Article Snippet: Next, a 5 μL solution containing 360 nM gRNA and 150 nM FAM-labeled 12PAM ds-DNA was added and incubated for 15 min at room temperature before acquiring the fluorescence polarization signal under a microplate reader (PerkinElmer, EnVision). .. Compounds were screened in duplicates and the data were processed to calculate the Z-score (a) values and plotted in Article Title: A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9 Article Snippet: Next, a 5 μL solution containing 360 nM of gRNA and 150 nM of FAM-labeled 12PAM DNA was added and incubated for 15 min at room temperature before measuring the fluorescence polarization signal with a microplate reader (Envision, PerkinElmer). .. Compounds were screened in duplicate, data were processed to calculate the Z-score (( x − μ)/ σ ) values and the values were plotted using the Article Title: A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1. Article Snippet: The von Hippel–Lindau tumor suppressor gene product (pVHL) is an E3 ligase substrate receptor that binds proline-hydroxylated hypoxia-inducible factor HIF1α, leading to its ubiquitin-dependent degradation.. By using protein arrays, we identified a small molecule that binds the HIF1α-binding pocket on pVHL and functions as a molecular glue degrader of the neosubstrate cysteine dioxygenase (CDO1) by recruiting it into the VHL– Cullin–RING E3 ligase complex and leading to its selective degradation.. The CDO1-binding region involved in VHL recruitment was characterized through a combination of mutagenesis and protein–protein docking coupled with molecular-dynamics-based solvation analysis. Article Title: DNA-encoded library-enabled discovery of proximity-inducing small molecules. Article Snippet: Small molecules that induce protein–protein associations represent powerful tools to modulate cell circuitry.. We sought to develop a platform for the direct discovery of compounds able to induce association of any two preselected proteins, using the E3 ligase von Hippel–Lindau (VHL) and bromodomains as test systems.. Leveraging the screening power of DNA-encoded libraries (DELs), we synthesized ~1 million DNA-encoded compounds that possess a VHL-targeting ligand, a variety of connectors and a diversity element generated by split-and-pool combinatorial chemistry. Activity Assay:Article Title: DNA-encoded library-enabled discovery of proximity-inducing small molecules. Article Snippet: Small molecules that induce protein–protein associations represent powerful tools to modulate cell circuitry.. We sought to develop a platform for the direct discovery of compounds able to induce association of any two preselected proteins, using the E3 ligase von Hippel–Lindau (VHL) and bromodomains as test systems.. Leveraging the screening power of DNA-encoded libraries (DELs), we synthesized ~1 million DNA-encoded compounds that possess a VHL-targeting ligand, a variety of connectors and a diversity element generated by split-and-pool combinatorial chemistry. Generated:Article Title: DNA-encoded library-enabled discovery of proximity-inducing small molecules. Article Snippet: Small molecules that induce protein–protein associations represent powerful tools to modulate cell circuitry.. We sought to develop a platform for the direct discovery of compounds able to induce association of any two preselected proteins, using the E3 ligase von Hippel–Lindau (VHL) and bromodomains as test systems.. Leveraging the screening power of DNA-encoded libraries (DELs), we synthesized ~1 million DNA-encoded compounds that possess a VHL-targeting ligand, a variety of connectors and a diversity element generated by split-and-pool combinatorial chemistry. other:Article Title: CRISPR protein inhibitors Article Snippet: Cells were resuspended in RIPA total cell lysis buffer (abcam) and incubated at 4° C. for 10 min. |